CAR-T therapy puts lupus patients in full remission

Five lupus patients in England have entered remission after receiving CAR T-cell therapy, a treatment that genetically modifies a patient's own immune cells to stop attacking healthy tissue. Doctors say none of the trial participants have needed any medication to manage their condition since treatment — a remarkable outcome for a disease that typically requires lifelong drug management. The NHS trial marks the first time this approach has been used against a chronic autoimmune disease rather than cancer.